Measurement of Some non-routine Markers in Patients with Chronic Kidney Disease

Chronic kidney disease has an indirect effect on global disorder and death by raising the risks of morbidityand mortality . This study included (60) patient diagnosed chronic renal failure; it also (25)healthy subjects as control In population age ranged from (14-65 years) old who visited Al-BasrahTeaching Hospital in Basrah throughout period October 2020 to February 2021. Enzyme-LinkedImmunosorbent Assay (ELISA) was used measure human serum soluble alpha klotho proteins , irisin andcystatin C The results showed that there is a high significant difference (P value < 0.01) levels betweenCKD patients for following : Soluble-a-klotho protein; Irisin (ng/ml) ; Cystatin-C (ng/ml).There decrease (ng/ml)among different stages chronickidney same table revealed increase <0.01) protein among respectively) Thestudy concluded remarkable level andirisin cystatin with these differences arepositively correlated glomerular filtration rate